Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012

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Severe sepsis and septic shock are major healthcare problems, affecting millions of people around the world each year, killing one in four (and often more), and increasing in incidence. 

Similar to polytrauma, acute myocardial infarction, or stroke, the speed and appropriateness of therapy administered in the initial hours after severe sepsis develops are likely to influence outcome. The recommendations in this document are intended to provide guidance for the clinician caring for a patient with severe sepsis or septic shock.

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